Down-Regulation of Renal Klotho Expression by Shiga Toxin 2
نویسندگان
چکیده
منابع مشابه
Down-regulation of renal klotho expression by Shiga toxin 2.
BACKGROUND/AIMS Shiga toxin 2 may trigger classical hemolytic uremic syndrome (HUS) eventually leading to renal failure. Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney is involved in the regulation of renal phosphate excretion and also retains renal protective effects. Renal failure is associated with renal depletion of klotho. The present study explored the in...
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ژورنال
عنوان ژورنال: Kidney and Blood Pressure Research
سال: 2014
ISSN: 1423-0143,1420-4096
DOI: 10.1159/000368457